ABSTRACT
Objective To investigate the clinical effect of thoracoscopic lobectomy in the treatment of elderly patients with non -small cell lung cancer .Methods 120 elderly patients with non -small cell lung cancer were selected as study objects ,and they were randomly divided into study group ( 60 cases ) and control group ( 60 cases ) according to the digital table .The control group was treated with traditional thoracic lobectomy .The study group was treated with thoracoscopic lobectomy .The surgical related indicators , postoperative pain , cardiopulmonary function , postoperative complications and clinical efficacy were compared between the two groups .Results The blood loss of the study group was (138.44 ±41.53)mL,which was less than (327.83 ±54.61)mL of the control group,and the postoperative drainage was (1290.28 ±129.37)mL in the study group,which was less than (1643.19 ±231.27)mL in the control group.The operation time and hospitalization time of the study group were (145.72 ±19.65) min, (7.43 ±1.59)d,respectively,which were shorter than (243.26 ±50.38)min,(10.35 ±2.34)d of the control group (t=21.383,10.316,13.972,7.995,all P<0.05).1,3,7 days after surgery,the VAS scores of the study group were significantly lower than those of the control group [(7.57 ±1.63) vs.(8.76 ±2.06),(5.46 ±0.82) vs.(6.68 ± 1.53),(2.51 ±0.41) vs.(4.94 icant difference in cardiopulmonary function between the two groups before treatment ( t =0.207,0.287,1.112, 0.137,all P>0.05).After treatment,the heart rate(HR) and the carbon monoxide diffusion (DLCO) of the study group were significantly lower than those of the control group [(83.27 ±12.85)times/min vs.(95.38 ±15.6)times/min,(67.49 ±6.84)％vs.(71.43 ±5.91)％],the FEV1 and mean ventilation volume(MVV) of the study group were significantly higher than those of the control group [(1.67 ±0.25)L vs.(1.42 ±0.10)L,(74.34 ±0.56)％vs.(63.25 ±0.51)％],and the differences were statistically significant (t=4.636,3.376,7.192,113.413,all P<0.05).The incidence rate of postoperative complications in the study group was lower than that in the control group (1.67％vs.11.67％,χ2 =4.821,P<0.05).There was no statistically significant difference between the two groups in median survival time(19.24 months vs.19.49 months,u=0.571,P>0.05).There was no statistically significant difference in the disease free survival rate between the two groups (P>0.05).Conclusion Thoracoscopic lobectomy has less effect on cardiopulmonary function in elderly patients with non -small cell lung cancer .The short -term curative effect is better than traditional thoracic lobectomy ,but the long-term curative effect is similar .